Description

Carbamic Acid, [(1R)-4-Oxo-2-Cyclohexen-1-Yl]-, 1,1-Dimethylethyl Ester (9Ci) is a chiral, protected carbamate derivative featuring a cyclohexenone scaffold, serving as a critical synthetic intermediate. This compound is valued for its role in constructing complex molecular architectures, particularly in the synthesis of biologically active molecules and chiral ligands. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for advanced organic synthesis and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Utilized as a precursor for chiral auxiliaries, catalysts, or ligands in enantioselective catalytic reactions.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Fine Chemical Synthesis: Used in the production of specialty chemicals, agrochemicals, and advanced materials requiring high stereochemical purity.
• Academic Research: A valuable reagent for methodological development in organic chemistry and total synthesis of natural products.

Basic Information

Product Name	Carbamic Acid, [(1R)-4-Oxo-2-Cyclohexen-1-Yl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	455330-42-4
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	(1R)-4-Oxo-2-cyclohexen-1-yl tert-butylcarbamate; tert-Butyl N-[(1R)-4-oxo-2-cyclohexen-1-yl]carbamate; (R)-tert-Butyl (4-oxocyclohex-2-en-1-yl)carbamate; (R)-N-Boc-4-oxo-2-cyclohexenylamine; (1R)-4-Oxo-2-cyclohexenylcarbamic acid tert-butyl ester; (R)-tert-Butyl 4-oxocyclohex-2-enecarbamate; 455330-42-4; tert-Butyl ((1R)-4-oxocyclohex-2-en-1-yl)carbamate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request. Our quality management system supports development under cGMP guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.