Description

tert-Butyl 4-(3-(Trifluoromethyl)Phenyl)-5,6-Dihydropyridine-1(2H)-Carboxylate (Wxg03392) is a high-purity, advanced pharmaceutical intermediate characterized by its dihydropyridine core and trifluoromethylphenyl moiety. This compound is of significant value for medicinal chemistry research and development, offering a versatile scaffold for the synthesis of novel bioactive molecules. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and agrochemical industries for constructing complex target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of novel active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Process Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Item	Information
Product Name	tert-Butyl 4-(3-(Trifluoromethyl)Phenyl)-5,6-Dihydropyridine-1(2H)-Carboxylate (Wxg03392)
CAS No.	454228-69-4
Molecular Formula	C17H20F3NO2
Molecular Weight	327.34 g/mol
Synonyms	1-Boc-4-(3-(Trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyridine; tert-Butyl 4-[3-(trifluoromethyl)phenyl]-3,6-dihydro-2H-pyridine-1-carboxylate; 1,2,3,6-Tetrahydro-1-[(1,1-dimethylethoxy)carbonyl]-4-[3-(trifluoromethyl)phenyl]pyridine; 4-(3-Trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine-1-carboxylic acid tert-butyl ester; Wxg03392; BOC-4-(3-TFM-phenyl)-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-(Trifluoromethyl)Phenyl)-5,6-Dihydropyridine-1(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.