Description

2,2,2-Trichloro-1-[4-(4-Methylbenzoyl)-1H-Pyrrol-2-Yl]-1-Ethanone CAS NO 453557-68-1 is a specialized organic compound featuring a trichloroacetyl group linked to a substituted pyrrole core. This structure makes it a valuable and versatile advanced pharmaceutical intermediate and key building block in synthetic organic chemistry. It is primarily utilized by research institutions and industrial manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Research: Used as a building block for developing new-generation herbicides and fungicides with specific modes of action.
• Material Science: Employed in the research and production of specialty polymers and organic electronic materials due to its unique electron-withdrawing properties.
• Chemical Synthesis: Acts as a versatile reagent for introducing the trichloroacetyl group into complex molecular frameworks, facilitating further functionalization.
• Academic & R&D: Essential for medicinal chemistry programs and organic synthesis research in university and corporate laboratories.

Basic Information

Product Name	2,2,2-Trichloro-1-[4-(4-Methylbenzoyl)-1H-Pyrrol-2-Yl]-1-Ethanone
CAS No.	453557-68-1
Molecular Formula	C14H10Cl3NO2
Molecular Weight	330.59 g/mol
Synonyms	1-(4-(4-Methylbenzoyl)-1H-pyrrol-2-yl)-2,2,2-trichloroethanone; 2,2,2-Trichloro-1-(4-(4-methylbenzoyl)-1H-pyrrol-2-yl)ethanone; 2,2,2-Trichloro-1-[4-(4-methylbenzoyl)-1H-pyrrol-2-yl]ethanone; Trichloroacetyl pyrrole derivative; 4-(4-Methylbenzoyl)-2-(trichloroacetyl)-1H-pyrrole
EINECS	Contact for details

Quality Control

Our 2,2,2-Trichloro-1-[4-(4-Methylbenzoyl)-1H-Pyrrol-2-Yl]-1-Ethanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles as verified by HPLC, GC, NMR, and IR spectroscopy. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.