Description

4-(6-Bromoimidazo[1,2-A]Pyridin-3-Yl)Pyrimidin-2-Amine (Wxc05190) is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is a critical building block in modern medicinal chemistry, valued for its fused heterocyclic structure that serves as a core scaffold in drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in oncology and targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of potent and selective kinase inhibitors, a major class of oncology drugs.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Chemical Biology Probes: Employed in the design of chemical probes to study and validate novel biological targets and mechanisms of action.
• Contract Research & Development (CRO/CDMO): Supplied to contract research and manufacturing organizations for client-specific synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-(6-Bromoimidazo[1,2-A]Pyridin-3-Yl)Pyrimidin-2-Amine (Wxc05190)
CAS No.	453510-84-4
Molecular Formula	C11H8BrN5
Molecular Weight	290.12 g/mol
Synonyms	4-(6-Bromoimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-amine; WXC-05190; WXC05190; 2-Pyrimidinamine, 4-(6-bromoimidazo[1,2-a]pyridin-3-yl)-; 4-(6-Bromo-imidazo[1,2-a]pyridin-3-yl)-pyrimidin-2-ylamine; 453510-84-4; 4-(6-Bromoimidazo[1,2-a]pyridin-3-yl)-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 4-(6-Bromoimidazo[1,2-A]Pyridin-3-Yl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.