Description

1H-Indene-4-Carboxylic Acid, 2,3,5,6,7,7A-Hexahydro-6,7-Dihydroxy-, Methyl Ester, (6R,7S,7Ar)-Rel- (9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral building block in the development of complex, biologically active molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new drug candidates, particularly for complex target molecules.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides where specific spatial orientation is crucial for activity.
• Fine Chemical Production: Acts as a specialized building block for synthesizing complex fragrances, flavors, and other high-value specialty chemicals.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in asymmetric synthesis and natural product analog development.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing manufacturing processes for target compounds in pilot plants.

Basic Information

Product Name	1H-Indene-4-Carboxylic Acid, 2,3,5,6,7,7A-Hexahydro-6,7-Dihydroxy-, Methyl Ester, (6R,7S,7Ar)-Rel- (9Ci)
CAS No.	452976-62-4
Molecular Formula	C12H18O4
Molecular Weight	226.27 g/mol
Synonyms	rel-(6R,7S,7aR)-Hexahydro-6,7-dihydroxy-1H-indene-4-carboxylic acid methyl ester; Methyl (6R,7S,7aR)-rel-2,3,5,6,7,7a-hexahydro-6,7-dihydroxy-1H-indene-4-carboxylate; (6R,7S,7aR)-rel-2,3,5,6,7,7a-Hexahydro-6,7-dihydroxy-1H-indene-4-carboxylic Acid Methyl Ester; 452976-62-4; Methyl ester of 1H-Indene-4-carboxylic acid, 2,3,5,6,7,7a-hexahydro-6,7-dihydroxy-, (6R,7S,7aR)-rel-; Chiral hexahydroindenediol methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the needs of cGMP-compliant development and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.