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4-Chloropyridin-3-Ylboronic Acid, Pinacol Ester 98 CAS NO 452972-15-5


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CAS No.:452972-15-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Chloropyridin-3-Ylboronic Acid, Pinacol Ester 98 is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and fine chemical synthesis.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing functionalized pyridine scaffolds.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific chloropyridine motifs.
  • Material Science: Serves as a building block for creating organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
  • Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex molecular architectures.
  • Ligand Synthesis: Employed in the preparation of specialized ligands used in homogeneous catalysis and coordination chemistry.

Basic Information

Item Details
Product Name 4-Chloropyridin-3-Ylboronic Acid, Pinacol Ester 98
CAS No. 452972-15-5
Molecular Formula C11H15BClNO2
Molecular Weight 239.51 g/mol
Synonyms 4-Chloro-3-pyridinylboronic acid pinacol ester; (4-Chloropyridin-3-yl)boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-chloropyridine; 4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Chloro-3-pyridylboronic acid pinacol ester; 452972-15-5; 4-Chloro-3-pyridinylboronic acid, pinacol ester
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Quality Control

Our 4-Chloropyridin-3-Ylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure a minimum purity of 98% and compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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