Description

4-Chloro3-Pyridylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients, advanced polymers, and electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, including OLEDs and conductive polymers.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex pyridine-containing heterocycles.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Bioconjugation: Facilitates the site-specific modification of biomolecules for diagnostic and therapeutic applications.

Basic Information

Product Name	4-Chloro3-Pyridylboronic Acid
CAS No.	452972-10-0
Molecular Formula	C5H5BClNO2
Molecular Weight	157.36 g/mol
Synonyms	(4-Chloro-3-pyridinyl)boronic acid; 4-Chloro-3-pyridineboronic acid; 3-Pyridineboronic acid, 4-chloro-; 4-Chloro-3-pyridylboronic acid pinacol ester (common derivative); 4-Chloro-3-boronopyridine; Boronic acid, B-(4-chloro-3-pyridinyl)-; 452972-10-0; 4-Cl-3-PyB(OH)2
EINECS	Contact for details

Quality Control

Our 4-Chloro3-Pyridylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to cGMP standards where applicable to meet the stringent requirements of our global clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.