Description

2-Bromopyridin-3-Ylboronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery, active ingredient synthesis, and the development of functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling: Serves as the boronic acid component for forming carbon-carbon bonds, enabling the introduction of the 2-bromo-3-pyridyl moiety into target molecules.
• Chemical Biology & Medicinal Chemistry: Utilized in library synthesis for high-throughput screening and structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	2-Bromopyridin-3-Ylboronic Acid
CAS No.	452972-08-6
Molecular Formula	C5H5BBrNO2
Molecular Weight	201.82 g/mol
Synonyms	(2-Bromopyridin-3-yl)boronic Acid; 3-Borono-2-bromopyridine; 2-Bromo-3-pyridineboronic Acid; 2-Bromo-3-pyridinylboronic Acid; 2-Bromo-3-pyridylboronic Acid; B-(2-Bromo-3-pyridinyl)boronic Acid; 452972-08-6
EINECS	Contact for details

Quality Control

Our 2-Bromopyridin-3-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.