Description

4-Methyl-2-(4-Trifluoromethyl-Phenyl)-Pyridine is a high-value, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethylphenyl group, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the trifluoromethyl group imparts desired biological activity and environmental persistence.
• Ligand Precursor: Serves as a starting material for synthesizing specialized ligands used in catalysis and material science.
• Functional Material Research: Employed in the development of organic electronic materials, such as OLEDs, due to its electron-deficient aromatic system.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems.

Basic Information

Product Name	4-Methyl-2-(4-Trifluoromethyl-Phenyl)-Pyridine
CAS No.	452342-99-3
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	2-(4-(Trifluoromethyl)phenyl)-4-picoline; 4-Methyl-2-[4-(trifluoromethyl)phenyl]pyridine; 2-(4-Trifluoromethylphenyl)-4-methylpyridine; 4-Methyl-2-(α,α,α-trifluoro-p-tolyl)pyridine; 2-(4-Trifluoromethylphenyl)-4-picoline
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-(4-Trifluoromethyl-Phenyl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions; ensure it is stored separately from such materials to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.