Description

tert-Butyl Vinylsulfonylcarbamate is a specialized organic building block featuring a reactive vinyl sulfone group protected by a tert-butyl carbamate moiety. This compound matters as a versatile intermediate for the synthesis of more complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel sulfonamide-based scaffolds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting protease enzymes or requiring sulfonamide pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced activity and selectivity.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for introducing sulfone groups into polymers to alter thermal and chemical resistance.
• Bioconjugation Chemistry: The vinyl sulfone group can undergo Michael addition reactions with thiols, making it useful for labeling proteins, peptides, and other biomolecules.
• Material Science: Employed in the creation of advanced functional materials, such as coatings, adhesives, and resins with specific performance characteristics.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.

Basic Information

Product Name	tert-Butyl Vinylsulfonylcarbamate
CAS No.	452341-63-8
Molecular Formula	C7H13NO4S
Molecular Weight	207.25 g/mol
Synonyms	tert-Butyl N-(vinylsulfonyl)carbamate; Carbamic acid, N-(ethenesulfonyl)-, 1,1-dimethylethyl ester; Vinylsulfonylcarbamic acid tert-butyl ester; 1,1-Dimethylethyl N-ethenesulfonylcarbamate; BOC-Vinylsulfonamide; tert-Butyl vinylsulfonylcarbamate; N-(Vinylsulfonyl)carbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl Vinylsulfonylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.