Description

Pyridine, 2-Ethynyl-5-Nitro- (9Ci) is a specialized heterocyclic building block characterized by its nitro and ethynyl functional groups on the pyridine core. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures via click chemistry and cross-coupling reactions. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the discovery of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders and infectious diseases.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers and conductive materials.
• Ligand Synthesis: Employed in the creation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes.
• Academic & Industrial R&D: A versatile building block for methodological development and discovery chemistry in laboratory settings.

Basic Information

Product Name	Pyridine, 2-Ethynyl-5-Nitro- (9Ci)
CAS No.	452333-53-8
Molecular Formula	C7H4N2O2
Molecular Weight	148.12 g/mol
Synonyms	2-Ethynyl-5-nitropyridine; 5-Nitro-2-ethynylpyridine; 2-Ethynyl-5-nitro-pyridine; 5-Nitro-2-pyridylacetylene; 2-(Ethynyl)-5-nitropyridine; 452333-53-8 (CAS); 2-Ethynyl-5-nitro-pyridine (9CI)
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 2-Ethynyl-5-Nitro- (9Ci) is produced and controlled under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure consistency and compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store this material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.