Description

Furo[3,4-B]Pyridin-7(2H)-One, Hexahydro-5-Methyl-, (4Ar,7Ar)-Rel- (9Ci) is a high-purity, stereochemically defined heterocyclic compound with the CAS number 452331-20-3. This advanced pharmaceutical intermediate is valued for its complex fused-ring structure, which serves as a critical building block in modern synthetic chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to construct intricate molecular architectures due to its fused furopyridinone core.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery pipelines.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring high stereochemical purity and defined molecular frameworks.

Basic Information

Product Name	Furo[3,4-B]Pyridin-7(2H)-One, Hexahydro-5-Methyl-, (4Ar,7Ar)-Rel- (9Ci)
CAS No.	452331-20-3
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	rel-(4aR,7aR)-Hexahydro-5-methylfuro[3,4-b]pyridin-7(2H)-one; 5-Methylhexahydrofuro[3,4-b]pyridin-7(2H)-one; (4aR,7aR)-5-Methylhexahydro-2H-furo[3,4-b]pyridin-7-one; Furo[3,4-b]pyridine-7(2H)-one, hexahydro-5-methyl-, (4aR,7aR)-rel-; 452331-20-3; Hexahydro-5-methylfuro[3,4-b]pyridin-7(2H)-one (rel-(4aR,7aR)-form)
EINECS	Contact for details

Quality Control

Our Furo[3,4-B]Pyridin-7(2H)-One, Hexahydro-5-Methyl-, (4Ar,7Ar)-Rel- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.