Description

4-(Pyridin-2-Yldisulfanyl)Pentanoic Acid is a specialized organic compound featuring a disulfide linkage to a pyridine ring, making it a valuable heterocyclic building block and reagent. This compound is significant for its role in chemical synthesis, particularly in the development of pharmaceuticals and advanced materials where controlled disulfide bond formation is critical. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, bioconjugation, and the synthesis of novel functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting cysteine-containing proteins or requiring disulfide-based prodrug strategies.
• Bioconjugation Reagent: Used for the site-specific modification of peptides, proteins, and antibodies, enabling the attachment of payloads, labels, or polymers via disulfide exchange reactions.
• Chemical Research & Development: Acts as a versatile building block in organic synthesis for constructing complex heterocyclic systems and introducing functional handles for further derivatization.
• Material Science: Employed in the development of smart polymers and functional surfaces where reversible disulfide chemistry can impart dynamic, stimuli-responsive properties.
• Crosslinking Agent: Utilized in creating disulfide-crosslinked hydrogels or polymer networks for controlled drug delivery and tissue engineering applications.

Basic Information

Product Name	4-(Pyridin-2-Yldisulfanyl)Pentanoic Acid
CAS No.	452072-22-9
Molecular Formula	C10H13NO2S2
Molecular Weight	243.34 g/mol
Synonyms	4-[(2-Pyridinyl)dithio]pentanoic acid; 2-(2-Pyridinyldithio)pentanoic acid; 4-(Pyridin-2-yldithio)pentanoic acid; 4-(2-Pyridyldithio)pentanoic acid; 4-(2-Pyridinyldisulfanyl)pentanoic acid; Pentanoic acid, 4-[(2-pyridinyl)dithio]-; 452072-22-9
EINECS	Contact for details

Quality Control

Our 4-(Pyridin-2-Yldisulfanyl)Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be sensitive to moisture and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.