Description

1-(2-Aminopyridin-4-Yl)-2-(4-Fluorophenyl)-Ethanone is a high-purity organic building block featuring a unique pyridine-fluorophenyl ketone scaffold. This compound is valued for its role as a critical intermediate in the synthesis of complex pharmaceutical molecules and advanced agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, dyes, and functional organic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and biochemical tools for target validation studies.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up manufacturing under cGMP conditions.

Basic Information

Product Name	1-(2-Aminopyridin-4-Yl)-2-(4-Fluorophenyl)-Ethanone
CAS No.	452056-80-3
Molecular Formula	C₁₃H₁₁FN₂O
Molecular Weight	230.24 g/mol
Synonyms	4-Fluoro-β-(2-amino-4-pyridinyl)acetophenone; 2-Amino-4-(4-fluorobenzoyl)pyridine; 1-(2-Amino-4-pyridinyl)-2-(4-fluorophenyl)ethanone; 4'-Fluoro-2-amino-4-pyridyl acetophenone; 2-Amino-4-(4-fluorophenacyl)pyridine; 4-(2-Aminopyridin-4-yl)-4'-fluoroacetophenone; 452056-80-3
EINECS	Contact for details

Quality Control

Our 1-(2-Aminopyridin-4-Yl)-2-(4-Fluorophenyl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.