Description

6-Methyl-4-Trifluoromethyl-Pyridine-2-Carbaldehyde is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its trifluoromethyl and aldehyde functional groups make it an essential intermediate for creating complex molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Product Name	6-Methyl-4-Trifluoromethyl-Pyridine-2-Carbaldehyde
CAS No.	451459-25-9
Molecular Formula	C8H6F3NO
Molecular Weight	189.13 g/mol
Synonyms	2-Formyl-6-methyl-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-6-methyl-2-pyridinecarboxaldehyde; 6-Methyl-4-(trifluoromethyl)picolinaldehyde; 6-Methyl-4-(trifluoromethyl)pyridine-2-carboxaldehyde; 2-Pyridinecarboxaldehyde, 6-methyl-4-(trifluoromethyl)-; 6-Methyl-4-trifluoromethyl-2-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Every batch of 6-Methyl-4-Trifluoromethyl-Pyridine-2-Carbaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. Due to its hygroscopic and easily oxidized nature, the container must be kept sealed and allowed to reach ambient temperature before opening to prevent moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.