Description

(6-Methyl-4-Trifluoromethyl-Pyridin-2-Yl)-Methanol is a high-value fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its core value lies in the trifluoromethyl group, which imparts unique physicochemical properties such as enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated organic materials, such as liquid crystals or polymers with specific electronic or surface properties.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways due to its fluorine tags.
• Custom Synthesis and R&D: A versatile starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	(6-Methyl-4-Trifluoromethyl-Pyridin-2-Yl)-Methanol
CAS No.	451459-23-7
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-(Hydroxymethyl)-6-methyl-4-(trifluoromethyl)pyridine; (6-Methyl-4-(trifluoromethyl)pyridin-2-yl)methanol; 4-(Trifluoromethyl)-6-methyl-2-pyridinemethanol; 2-Pyridinemethanol, 6-methyl-4-(trifluoromethyl)-; 6-Methyl-4-trifluoromethyl-pyridin-2-yl-methanol
EINECS	Contact for details

Quality Control

Our (6-Methyl-4-Trifluoromethyl-Pyridin-2-Yl)-Methanol is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with ISO standards and meets the stringent requirements of pharmaceutical and agrochemical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.