Description

5-Bromo-1,6-Dimethyl-2-Oxo-1,2-Dihydro-Pyridine-3-Carbonitrile is a high-purity, versatile heterocyclic building block with a bromine substituent ideal for further functionalization. This compound is critical for research and development in advanced organic synthesis, particularly in the construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive pyridine core.
• Material Science: Acts as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Synthesis: The bromine atom provides an excellent handle for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), enabling rapid diversification of the molecular scaffold.
• Academic & Contract Research: A valuable reagent for universities and CROs exploring new heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	5-Bromo-1,6-Dimethyl-2-Oxo-1,2-Dihydro-Pyridine-3-Carbonitrile
CAS No.	450841-30-2
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	5-Bromo-1,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile; 3-Cyano-5-bromo-1,6-dimethyl-2(1H)-pyridinone; 5-Bromo-1,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; 5-Bromo-1,6-dimethyl-2-oxo-1,4-dihydro-3-pyridinecarbonitrile (tautomer); 450841-30-2; 1,2-Dihydro-5-bromo-1,6-dimethyl-2-oxo-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,6-Dimethyl-2-Oxo-1,2-Dihydro-Pyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.