Description

Benzoic Acid, 3-Bromo-2-Iodo-, Ethyl Ester is a halogenated aromatic ester building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists working on new active ingredients, where its unique substitution pattern enables precise structural modifications. The product is supplied to meet the stringent purity and consistency requirements of modern discovery and scale-up laboratories.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where halogenated aromatics are common structural motifs.
• Material Science: Serves as a monomer or precursor for specialized polymers and liquid crystals with unique electronic or optical properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Stille) due to the presence of both bromo and iodo substituents, allowing for sequential functionalization.
• Chemical Synthesis Reference Standard: Used as a high-purity standard for analytical method development and validation in QC laboratories.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in organic reaction mechanisms and new synthetic methodology.

Basic Information

Product Name	Benzoic Acid, 3-Bromo-2-Iodo-, Ethyl Ester
CAS No.	450412-26-7
Molecular Formula	C9H8BrIO2
Molecular Weight	354.97 g/mol
Synonyms	Ethyl 3-Bromo-2-iodobenzoate; 3-Bromo-2-iodobenzoic Acid Ethyl Ester; Benzoic acid, 3-bromo-2-iodo-, ethyl ester; 2-Iodo-3-bromobenzoic Acid Ethyl Ester; Ethyl 2-Iodo-3-bromobenzoate; 450412-26-7; AI3-28500
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-Bromo-2-Iodo-, Ethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.