Description

6-(4-Methylpiperazin-1-Yl)Pyridine-2-Carboxylic Acid is a high-value heterocyclic carboxylic acid building block, essential for advanced pharmaceutical and agrochemical synthesis. Its core value lies in its dual functionality, combining a reactive carboxylic acid group with a substituted piperazine moiety, enabling the construction of complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical industry for creating novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific piperazine-based structures for bioactivity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Utilized as a monomer or functional additive in the development of specialty polymers with tailored properties.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	6-(4-Methylpiperazin-1-Yl)Pyridine-2-Carboxylic Acid
CAS No.	450368-30-6
Molecular Formula	C12H15N3O2
Molecular Weight	233.27 g/mol
Synonyms	6-(4-Methyl-1-piperazinyl)-2-pyridinecarboxylic acid; 2-Pyridinecarboxylic acid, 6-(4-methyl-1-piperazinyl)-; 6-(4-Methylpiperazin-1-yl)picolinic acid; 6-(N-Methylpiperazinyl)picolinic acid; 6-(4-Methylpiperazino)pyridine-2-carboxylic acid; 6-(4-Methylpiperazin-1-yl)pyridine-2-carboxylate; 450368-30-6 (CAS); MPCA (abbreviation)
EINECS	Contact for details

Quality Control

Our 6-(4-Methylpiperazin-1-Yl)Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.