Description

3-Pyridinecarboxylic Acid, 6-Ethynyl- (9Ci) is a specialized pyridine derivative featuring a carboxylic acid group and an ethynyl substituent, making it a valuable bifunctional building block for advanced synthesis. This compound is particularly significant for its role in the development of pharmaceutical intermediates and novel materials, where its unique structure enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules and functionalized ligands.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Building block for creating functionalized ligands in catalysis and metal-organic frameworks (MOFs).
• Precursor in agrochemical research for developing new crop protection agents.
• Starting material for the synthesis of advanced organic electronic materials and dyes.
• Use in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Component in the development of diagnostic agents and biochemical probes.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 6-Ethynyl- (9Ci)
CAS No.	450368-21-5
Molecular Formula	C8H5NO2
Molecular Weight	147.13 g/mol
Synonyms	6-Ethynylnicotinic Acid; 6-Ethynylpyridine-3-carboxylic Acid; 3-Carboxy-6-ethynylpyridine; 6-Ethynyl-3-pyridinecarboxylic Acid; 6-Ethynyl-3-picolinic Acid; 6-Ethynylnicotinate (acid form); 6-Ethynyl-3-carboxypyridine
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 6-Ethynyl- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.