Description

3-Pyridinecarboxamide,n-(2,3-Dihydro-1H-Inden-2-Yl)-,1-Oxide(9Ci) is a specialized heterocyclic compound featuring a pyridinecarboxamide core fused with an indane moiety and an N-oxide functional group. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its structural complexity offers significant potential for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop novel therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Ligand and Catalyst Development: The N-oxide and amide functionalities make it a candidate for developing chelating ligands in catalytic systems.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and protein interactions.
• Academic and Institutional R&D: A critical reagent for universities and research institutes conducting synthetic organic chemistry and drug discovery projects.

Basic Information

Item	Details
Product Name	3-Pyridinecarboxamide,n-(2,3-Dihydro-1H-Inden-2-Yl)-,1-Oxide(9Ci)
CAS No.	450351-31-2
Molecular Formula	C15H14N2O2
Molecular Weight	254.28 g/mol
Synonyms	N-(2,3-Dihydro-1H-inden-2-yl)nicotinamide 1-oxide; Nicotinamide, N-(2,3-dihydro-1H-inden-2-yl)-, 1-oxide; 3-Pyridinecarboxamide, N-(2,3-dihydro-1H-inden-2-yl)-, N-oxide; 2-(Nicotinoyl)indane N-oxide; Indane-2-nicotinamide N-oxide; CAS 450351-31-2
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxamide,n-(2,3-Dihydro-1H-Inden-2-Yl)-,1-Oxide(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.