Description

2-Chloro-n-(2,3-Dihydro-1H-Inden-2-Yl)Nicotinamide is a high-purity, synthetically derived organic compound featuring a nicotinamide core linked to a 2,3-dihydro-1H-indene moiety. This specific molecular architecture makes it a valuable chemical intermediate and pharmacological research tool, particularly in the development of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical synthesis facilities engaged in creating new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, especially those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Probe Development: Employed in the design and creation of molecular probes for studying enzyme function or protein-ligand interactions.
• Organic Synthesis: Acts as a versatile intermediate for constructing more complex heterocyclic compounds and functionalized indane derivatives.
• Agrochemical Research: Potential use as a precursor in the development of new active ingredients for crop protection products.
• Material Science: Can be utilized in the synthesis of specialty polymers or organic electronic materials due to its fused ring system.

Basic Information

Product Name	2-Chloro-n-(2,3-Dihydro-1H-Inden-2-Yl)Nicotinamide
CAS No.	450349-68-5
Molecular Formula	C15H13ClN2O
Molecular Weight	272.73 g/mol
Synonyms	2-Chloro-N-(2,3-dihydro-1H-inden-2-yl)nicotinamide; 2-Chloro-N-indan-2-ylnicotinamide; Nicotinamide, 2-chloro-N-(2,3-dihydro-1H-inden-2-yl)-; 450349-68-5; 2-Chloro-N-(indan-2-yl)pyridine-3-carboxamide; 3-Pyridinecarboxamide, 2-chloro-N-2,3-dihydro-1H-inden-2-yl-; 2-Chloro-N-(2,3-dihydro-1H-inden-2-yl)-3-pyridinecarboxamide
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-n-(2,3-Dihydro-1H-Inden-2-Yl)Nicotinamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard research-grade material typically meets high-purity specifications suitable for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.