Description

6-Chloro-4-(Methylamino)-Pyridine-3-Carboxylic Acid Ethyl Ester is a high-purity pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized heterocyclic core essential for constructing complex molecular architectures. This intermediate is primarily needed by pharmaceutical and agrochemical R&D departments for the development of new active ingredients, including potential kinase inhibitors and other biologically relevant compounds.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Building block for creating advanced crop protection agents and herbicides.
• Chemical Research: Versatile precursor for heterocyclic chemistry, enabling the synthesis of diverse pyridine-based libraries.
• Material Science: Potential monomer or functional additive in the development of specialty polymers and advanced materials.
• Contract Manufacturing: Supplied to CDMOs for use in custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	6-Chloro-4-(Methylamino)-Pyridine-3-Carboxylic Acid Ethyl Ester
CAS No.	449811-28-3
Molecular Formula	C10H13ClN2O2
Molecular Weight	228.68 g/mol
Synonyms	Ethyl 6-Chloro-4-(methylamino)nicotinate; 6-Chloro-4-(methylamino)nicotinic Acid Ethyl Ester; 4-(Methylamino)-6-chloropyridine-3-carboxylic Acid Ethyl Ester; 449811-28-3; Ethyl 6-chloro-4-(methylamino)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 6-chloro-4-(methylamino)-, ethyl ester; 6-Chloro-4-methylaminonicotinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-(Methylamino)-Pyridine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) are available upon request, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The product may be hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.