Description

5-(Bromomethyl)-2-Nitropyridine is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and an electron-withdrawing nitro substituent, makes it an indispensable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of organic electronic materials, such as conductive polymers and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Serves as an electrophilic partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	5-(Bromomethyl)-2-Nitropyridine
CAS No.	448968-52-3
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	2-Nitro-5-(bromomethyl)pyridine; 5-Bromomethyl-2-nitropyridine; 2-Pyridinecarbonitrile, 5-(bromomethyl)-2-nitro-; (2-Nitro-5-pyridinyl)methyl bromide; 5-(Bromomethyl)-2-nitro-pyridine; 2-Nitro-5-bromomethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 5-(Bromomethyl)-2-Nitropyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.