Description

2-Bromo-4-(3-Pyridin-2-Yl-1H-Pyrazol-4-Yl)-Pyridine is a high-value brominated heterocyclic compound featuring a pyridine-pyrazole core structure, serving as a critical synthetic intermediate. Its primary value lies in enabling the construction of complex molecules for pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in drug discovery, particularly for kinase inhibitor programs and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel drug candidates.
• Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study biological pathways and target validation.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Can be utilized in the synthesis of organic ligands for metal-organic frameworks (MOFs) or functional materials.

Basic Information

Product Name	2-Bromo-4-(3-Pyridin-2-Yl-1H-Pyrazol-4-Yl)-Pyridine
CAS No.	446880-81-5
Molecular Formula	C13H9BrN4
Molecular Weight	301.14 g/mol
Synonyms	2-Bromo-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridine; 4-(2-Bromopyridin-4-yl)-3-(2-pyridyl)-1H-pyrazole; 2-Bromo-4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]pyridine; Pyridine, 2-bromo-4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]-; 446880-81-5; 2-Bromo-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(3-Pyridin-2-Yl-1H-Pyrazol-4-Yl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.