Description

n-(5-Bromo-3-Methylpyridin-2-Yl)-2,2-Dimethylpropanamide is a high-purity brominated pyridine derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in providing a structurally defined, functionalized scaffold essential for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the pyridine core for bioactivity.
• Chemical Research & Development: Serves as a versatile precursor for further functionalization (e.g., cross-coupling reactions) in medicinal and synthetic chemistry.
• Ligand and Catalyst Preparation: Can be utilized to develop novel ligands for metal catalysis or as a component in organocatalysts.
• Material Science Research: Potential intermediate for creating functionalized organic materials and liquid crystals.

Basic Information

Product Name	n-(5-Bromo-3-Methylpyridin-2-Yl)-2,2-Dimethylpropanamide
CAS No.	446299-84-9
Molecular Formula	C11H15BrN2O
Molecular Weight	271.16 g/mol
Synonyms	2,2-Dimethyl-N-(5-bromo-3-methyl-2-pyridinyl)propanamide; 5-Bromo-3-methyl-N-(2,2-dimethylpropanoyl)pyridin-2-amine; N-(5-Bromo-3-methylpyridin-2-yl)pivalamide; Pivalic acid (5-bromo-3-methyl-2-pyridyl)amide; 446299-84-9; 5-Bromo-3-methyl-2-pivalamidopyridine
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-3-Methylpyridin-2-Yl)-2,2-Dimethylpropanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.