Description

1H-Pyrrolo[3,2-C]Pyridine, 7-Bromo-4-Methoxy- is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 446284-60-2. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its precise molecular structure which enables the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted small-molecule drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Synthesis: Used in the production of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-fidelity brominated heterocycles.

Basic Information

Item	Details
Product Name	1H-Pyrrolo[3,2-C]Pyridine, 7-Bromo-4-Methoxy-
CAS No.	446284-60-2
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	7-Bromo-4-methoxy-1H-pyrrolo[3,2-c]pyridine; 4-Methoxy-7-bromo-1H-pyrrolo[3,2-c]pyridine; 7-Bromo-4-methoxypyrrolo[3,2-c]pyridine; 1H-Pyrrolo[3,2-c]pyridine, 7-bromo-4-methoxy-; 446284-60-2; 7-Br-4-MeO-pyrrolopyridine
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[3,2-C]Pyridine, 7-Bromo-4-Methoxy- adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.