Description

5-Bromo-3-Nitro-2-(1H-Pyrazol-1-Yl)Pyridine 98% is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring bromo, nitro, and pyrazolyl substituents on a pyridine core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and specialty chemicals.

Application

This specialized pyridine derivative serves as a critical intermediate in various research and industrial synthesis pathways. Key application areas include:

• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly as a scaffold for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Serves as a key building block for creating novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science Research: Employed in the synthesis of organic ligands for catalysis, metal-organic frameworks (MOFs), and advanced polymeric materials.
• Chemical Biology Probes: Useful for constructing molecular probes and tags to study biological processes and protein interactions.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create more complex biaryl structures.
• Nucleophilic Aromatic Substitution: The nitro group and halogen allow for sequential functionalization, enabling precise molecular editing.

Basic Information

Product Name	5-Bromo-3-Nitro-2-(1H-Pyrazol-1-Yl)Pyridine 98%
CAS No.	446284-40-8
Molecular Formula	C8H5BrN4O2
Molecular Weight	285.06 g/mol
Synonyms	5-Bromo-3-nitro-2-(1H-pyrazol-1-yl)pyridine; 2-(1H-Pyrazol-1-yl)-5-bromo-3-nitropyridine; Pyridine, 5-bromo-3-nitro-2-(1H-pyrazol-1-yl)-; 446284-40-8; 5-Br-3-NO2-2-PzPy
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Nitro-2-(1H-Pyrazol-1-Yl)Pyridine 98% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the specified 98% minimum purity and consistent impurity profile. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maximize stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.