Description

1H-Pyrrolo[2,3-C]Pyridine, 7-Bromo-4-Fluoro- is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This heterocyclic compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Kinase Inhibitor Development: Serves as a core scaffold for the research and production of potent and selective kinase inhibitors used in oncology and other therapeutic areas.
• Medicinal Chemistry Research: Utilized in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and safety profiles.
• Bioconjugation & Probe Synthesis: Can be functionalized for creating chemical probes and bioconjugates used in biochemical assays and diagnostic research.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial drug substances.

Basic Information

Product Name	1H-Pyrrolo[2,3-C]Pyridine, 7-Bromo-4-Fluoro-
CAS No.	446284-38-4
Molecular Formula	C7H4BrFN2
Molecular Weight	215.03 g/mol
Synonyms	7-Bromo-4-fluoro-1H-pyrrolo[2,3-c]pyridine; 4-Fluoro-7-bromo-1H-pyrrolo[2,3-c]pyridine; 7-Bromo-4-fluoro-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine, 7-bromo-4-fluoro-; 7-Bromo-4-fluoro-pyrrolo[2,3-c]pyridine; 4-Fluoro-7-bromo-pyrrolo[2,3-c]pyridine
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-C]Pyridine, 7-Bromo-4-Fluoro- adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for advanced synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and quantify impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.