Description

5-Bromo-2-Methoxy-Pyridin-n-Oxide is a versatile pyridine derivative and a valuable halogenated heterocyclic building block. This compound is of significant interest in advanced organic synthesis, particularly for the construction of complex molecules in pharmaceutical and agrochemical research. It serves as a key intermediate for medicinal chemists and process development scientists engaged in the discovery and scale-up of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogen and methoxy substituents for structural diversity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and functionalized polymers where the pyridine N-oxide moiety can modify electronic properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags to study biological processes and protein interactions.

Basic Information

Product Name	5-Bromo-2-Methoxy-Pyridin-n-Oxide
CAS No.	446284-14-6
Molecular Formula	C₆H₆BrNO₂
Molecular Weight	204.02 g/mol
Synonyms	5-Bromo-2-methoxypyridine 1-oxide; 2-Methoxy-5-bromopyridine N-oxide; 5-Bromo-2-methoxypyridine N-oxide; 5-Bromo-2-methoxypyridine oxide; Pyridine, 5-bromo-2-methoxy-, 1-oxide; 446284-14-6; 5-Br-2-MeO-Pyridine N-Oxide
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Methoxy-Pyridin-n-Oxide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.