Description

2-([3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]Amino)Acetohydrazide is a high-value, multifunctional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyridine and hydrazide structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl and chloro substituents for enhanced bioactivity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new heterocyclic chemistry, creating libraries of compounds for high-throughput screening.
• Material Science Precursor: Potential use in the synthesis of specialized ligands for catalysis or as a monomer for creating polymers with specific electronic or binding properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for client-specific projects.

Basic Information

Product Name	2-([3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]Amino)Acetohydrazide
CAS No.	446276-13-7
Molecular Formula	C8H6ClF3N4O
Molecular Weight	266.61 g/mol
Synonyms	2-[(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino]acetohydrazide; Acetohydrazide, 2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-; 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)acetohydrazide; 2-[[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino]acetohydrazide; 2-[(3-Chloro-5-(trifluoromethyl)-2-pyridyl)amino]acetohydrazide; 446276-13-7; 2-(3-Chloro-5-trifluoromethyl-pyridin-2-ylamino)-acetohydrazide
EINECS	Contact for details

Quality Control

Our 2-([3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]Amino)Acetohydrazide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed when not in use. Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.