Description

4'-(Aminomethyl)-Biphenyl-3-Carboxylic Acid Methyl Ester is a high-purity bifunctional organic intermediate featuring both an aromatic ester and a primary benzylamine group. This compound matters as a versatile building block for the synthesis of complex molecules, enabling the creation of advanced materials and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new compounds and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging its biphenyl core for biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced organic electronic materials due to its rigid biphenyl structure and modifiable functional groups.
• Polymer Modification: Employed to introduce aromatic amine functionalities into polymer chains, enhancing thermal stability and mechanical properties.
• Cross-coupling Reactions: The aromatic halide or boronic ester derivatives of this compound are valuable substrates in Suzuki and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology & Proteomics: Acts as a linker or spacer molecule in the design of probes, affinity tags, and bioconjugation reagents.

Basic Information

Product Name	4'-(Aminomethyl)-Biphenyl-3-Carboxylic Acid Methyl Ester
CAS No.	445492-67-1
Molecular Formula	C16H17NO2
Molecular Weight	255.31 g/mol
Synonyms	Methyl 4'-(aminomethyl)-[1,1'-biphenyl]-3-carboxylate; 3-Carbomethoxy-4'-aminomethylbiphenyl; [1,1'-Biphenyl]-3-carboxylic acid, 4'-(aminomethyl)-, methyl ester; 4'-(Aminomethyl)biphenyl-3-carboxylic acid methyl ester; Methyl 3-biphenylcarboxylate-4'-aminomethyl; Biphenyl-3-carboxylic acid, 4'-(aminomethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 4'-(Aminomethyl)-Biphenyl-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.