Description

3-Bromo-5-(Methylsulphonyl)Pyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it provides a reactive bromine atom and an electron-withdrawing methylsulfonyl group on a pyridine scaffold, enabling precise molecular construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for functionalized ligands in catalysis and for creating specialty polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Chemical Biology: Utilized as a probe or linker in bioconjugation and proteomics research.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers.

Basic Information

Product Name	3-Bromo-5-(Methylsulphonyl)Pyridine
CAS No.	445491-71-4
Molecular Formula	C7H8BrNO2S
Molecular Weight	250.11 g/mol
Synonyms	3-Bromo-5-(methylsulfonyl)pyridine; 5-Bromo-3-(methylsulfonyl)pyridine; Pyridine, 3-bromo-5-(methylsulfonyl)-; 3-Bromo-5-methanesulfonylpyridine; 445491-71-4; 3-Bromo-5-methylsulfonylpyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-(Methylsulphonyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is moisture-sensitive; ensure containers are sealed after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.