Description

3-Amino-6-Ethyl-n-[2-(4-Fluorophenyl)Ethyl]-5,6,7,8-Tetrahydrothieno[2,3-B]Quinoline-2-Carboxamide is a high-purity, complex heterocyclic organic compound serving as a critical advanced intermediate in modern pharmaceutical research and development. Its intricate molecular structure, featuring fused thienoquinoline and carboxamide moieties, makes it a valuable scaffold for designing novel bioactive molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Chemical Biology Probe: Used in academic and industrial research to study protein-ligand interactions and enzyme inhibition mechanisms due to its complex heterocyclic structure.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes during the optimization phase of Active Pharmaceutical Ingredient (API) manufacturing.
• Library Synthesis for High-Throughput Screening (HTS): Employed in medicinal chemistry to create focused libraries of analogs for biological activity screening.
• Reference Standard: Supplied as a high-purity compound for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	3-Amino-6-Ethyl-n-[2-(4-Fluorophenyl)Ethyl]-5,6,7,8-Tetrahydrothieno[2,3-B]Quinoline-2-Carboxamide
CAS No.	445268-94-0
Molecular Formula	C22H24FN3OS
Molecular Weight	397.51 g/mol
Synonyms	3-Amino-6-ethyl-N-[2-(4-fluorophenyl)ethyl]-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide; 3-Amino-6-ethyl-N-[2-(4-fluorophenyl)ethyl]-5,6,7,8-tetrahydro-4H-thieno[2,3-b]quinoline-2-carboxamide; 445268-94-0; Thieno[2,3-b]quinoline-2-carboxamide, 3-amino-6-ethyl-N-[2-(4-fluorophenyl)ethyl]-5,6,7,8-tetrahydro-; 3-Amino-6-ethyl-N-(2-(4-fluorophenyl)ethyl)-5,6,7,8-tetrahydro-4H-thieno[2,3-b]quinoline-2-carboxamide
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Ethyl-n-[2-(4-Fluorophenyl)Ethyl]-5,6,7,8-Tetrahydrothieno[2,3-B]Quinoline-2-Carboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support our clients' regulatory needs with traceable documentation and can supply material compliant with ICH guidelines for impurities in drug substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.