Description

4-Bromo-Dl-Phenylalanine Methyl Ester Hcl CAS NO 444726-88-9 is a halogenated phenylalanine derivative, a key chiral building block in organic synthesis. This compound is valued for its role in introducing the 4-bromophenyl moiety, a versatile functional handle for further cross-coupling reactions and structural modifications. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers for the synthesis of novel drug candidates, peptide mimetics, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders.
• Peptidomimetics Synthesis: Used to incorporate non-natural amino acid residues into peptide chains to enhance metabolic stability, bioavailability, and binding affinity.
• Chemical Biology Probes: Serves as a building block for creating labeled compounds and molecular probes used in biochemical and cellular studies.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks.
• Academic & Industrial Research: A standard reagent in organic chemistry laboratories for method development and exploring novel synthetic pathways.

Basic Information

Product Name	4-Bromo-Dl-Phenylalanine Methyl Ester Hcl
CAS No.	444726-88-9
Molecular Formula	C10H13BrNO2 • HCl
Molecular Weight	308.58 g/mol (Free base: 272.12)
Synonyms	Methyl 2-amino-3-(4-bromophenyl)propanoate hydrochloride; DL-4-Bromophenylalanine methyl ester hydrochloride; (RS)-2-Amino-3-(4-bromophenyl)propionic acid methyl ester hydrochloride; 4-Bromo-DL-phenylalanine methyl ester HCl; Methyl (RS)-2-amino-3-(4-bromophenyl)propionate hydrochloride; 4-Br-Phe-OMe • HCl; α-Amino-4-bromohydrocinnamic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Bromo-Dl-Phenylalanine Methyl Ester Hcl is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.