Description

1-(4-Cyanophenyl)-1H-Pyridin-2-One is a high-purity organic intermediate featuring a pyridinone core linked to a cyanophenyl group. This compound matters as a critical building block in modern pharmaceutical and agrochemical research, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drugs, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(4-Cyanophenyl)-1H-Pyridin-2-One
CAS No.	444002-96-4
Molecular Formula	C₁₂H₈N₂O
Molecular Weight	196.21 g/mol
Synonyms	1-(4-Cyanophenyl)pyridin-2(1H)-one; 2(1H)-Pyridinone, 1-(4-cyanophenyl)-; 1-(4-Cyanophenyl)-2(1H)-pyridinone; 1-(4-Cyanophenyl)-1H-pyridin-2-one; 4-(2-Oxo-2H-pyridin-1-yl)benzonitrile; 1-(p-Cyanophenyl)-2-pyridone
EINECS	Contact for details

Quality Control

Our 1-(4-Cyanophenyl)-1H-Pyridin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.