Description

3-Azido-5-(Chloromethyl)Pyridine is a versatile bifunctional heterocyclic building block containing both an azide and a chloromethyl group. This compound matters as a key intermediate for click chemistry and bioconjugation, enabling the efficient synthesis of complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly for targeted therapies and bioconjugates.
• Click Chemistry Reagent: The azide group enables efficient, high-yield Huisgen 1,3-dipolar cycloaddition reactions with alkynes for labeling and ligation.
• Bioconjugation Linker: Used to attach small molecules, dyes, or drugs to proteins, antibodies, or other biomolecules for diagnostic and therapeutic applications.
• Agrochemical Synthesis: Acts as a building block for creating new pesticides and herbicides with specific modes of action.
• Polymer & Materials Science: Incorporated into polymer backbones or as a cross-linking agent to create functional materials with tailored properties.
• Chemical Biology Probes: Utilized in the development of activity-based probes for studying enzyme function and metabolic pathways.

Basic Information

Item	Details
Product Name	3-Azido-5-(Chloromethyl)Pyridine
CAS No.	443964-36-1
Molecular Formula	C6H5ClN4
Molecular Weight	168.58 g/mol
Synonyms	5-(Chloromethyl)-3-azidopyridine; 3-Azido-5-(chloromethyl)pyridine; 5-(Chloromethyl)pyridin-3-yl azide; (Chloromethyl)-3-azidopyridine; Azidopyridine chloromethyl derivative
EINECS	Contact for details

Quality Control

Our 3-Azido-5-(Chloromethyl)Pyridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.