Description

Ethyl 2-(6-Bromo-2-Nitropyridin-3-Yloxy)Acetate is a high-purity, advanced pharmaceutical intermediate with the CAS number 443956-09-0. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise bromo- and nitro-substituted pyridine core. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its reactive halogen and nitro functional groups.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing more complex heterocyclic compounds and fine chemicals.
• Material Science Research: Investigated as a monomer or functional additive in the development of specialty polymers and advanced materials.
• Academic & R&D Laboratories: Serves as a standard reagent for methodological studies in synthetic organic chemistry and catalysis.

Basic Information

Product Name	Ethyl 2-(6-Bromo-2-Nitropyridin-3-Yloxy)Acetate
CAS No.	443956-09-0
Molecular Formula	C9H9BrN2O5
Molecular Weight	305.08 g/mol
Synonyms	Ethyl (6-Bromo-2-nitro-3-pyridyloxy)acetate; Acetic acid, 2-[(6-bromo-2-nitro-3-pyridinyl)oxy]-, ethyl ester; 3-Pyridinol, 6-bromo-2-nitro-, 2-(ethoxycarbonylmethyl) ether; 443956-09-0; Ethyl 2-((6-bromo-2-nitropyridin-3-yl)oxy)acetate
EINECS	Contact for details

Quality Control

Our Ethyl 2-(6-Bromo-2-Nitropyridin-3-Yloxy)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.