Description

6-Bromo-2-Nitro-Pyridin-3-Ol is a halogenated nitropyridine derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and nitro substituents on the pyridine ring, makes it a valuable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine core is a common structural motif.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.
• Academic and Industrial R&D: Used in research laboratories for method development and exploring new chemical reactions involving halogenated nitropyridines.

Basic Information

Product Name	6-Bromo-2-Nitro-Pyridin-3-Ol
CAS No.	443956-08-9
Molecular Formula	C5H3BrN2O3
Molecular Weight	218.99 g/mol
Synonyms	3-Hydroxy-6-bromo-2-nitropyridine; 6-Bromo-2-nitro-3-pyridinol; 6-Bromo-2-nitropyridin-3-ol; 2-Nitro-6-bromopyridin-3-ol; 6-Bromo-3-hydroxy-2-nitropyridine; 443956-08-9; 6-Br-2-NO2-3-OH-Pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Nitro-Pyridin-3-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support development and commercial projects requiring standards from laboratory to pilot plant scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.