Description

Methyl 2-Oxo-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Thiazine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used in research and development for constructing novel pyridothiazine-based heterocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in the discovery of new therapeutic agents.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs under GMP guidelines.
• Biochemical Research: Potential use as a reference standard or probe in biochemical assays investigating specific enzyme or receptor interactions.

Basic Information

Product Name	Methyl 2-Oxo-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Thiazine-7-Carboxylate
CAS No.	443955-71-3
Molecular Formula	C9H8N2O3S
Molecular Weight	224.24 g/mol
Synonyms	Methyl 2-oxo-2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazine-7-carboxylate; 7-Methoxycarbonyl-2,3-dihydro-2-oxo-1H-pyrido[2,3-b][1,4]thiazine; 1H-Pyrido[2,3-b][1,4]thiazine-7-carboxylic acid, 2,3-dihydro-2-oxo-, methyl ester; Methyl 2-oxo-1,2,3,4-tetrahydropyrido[2,3-b][1,4]thiazine-7-carboxylate; 443955-71-3; Methyl 1,4-thiazino[2,3,4-hi]quinoline-7-carboxylate derivative
EINECS	Contact for details

Quality Control

Our Methyl 2-Oxo-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Thiazine-7-Carboxylate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.