Description

2-Isocyanomethyltetra-Hydrofurane is a specialized heterocyclic isocyanate derivative, serving as a versatile and reactive building block in advanced organic synthesis. Its core value lies in enabling the efficient construction of complex molecular architectures, particularly in the development of novel polymers and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty polymer industries seeking to innovate with precise and reliable chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing tetrahydrofuran and urethane/urea moieties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its reactive isocyanate group facilitates the creation of potent active ingredients.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes, polyureas, and other high-performance polymers with tailored properties.
• Chemical Research (R&D): A valuable reagent for academic and industrial research in organic and medicinal chemistry for exploring new synthetic pathways.
• Material Science: Employed in the development of advanced coatings, adhesives, and elastomers that require specific chemical resistance and durability.

Basic Information

Product Name	2-Isocyanomethyltetra-Hydrofurane
CAS No.	443890-11-7
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	2-Isocyanomethyltetrahydrofuran; Tetrahydrofuran-2-ylmethyl isocyanate; 2-(Isocyanomethyl)tetrahydrofuran; (Tetrahydrofuran-2-yl)methyl isocyanate; 2-Tetrahydrofuranylmethyl isocyanate; THF-2-ylmethyl isocyanate; 443890-11-7; 2-Isocyanomethyl-tetrahydrofuran
EINECS	Contact for details

Quality Control

Our 2-Isocyanomethyltetra-Hydrofurane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including assay by HPLC, identification by FT-IR, and control of key impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Density (at 20°C)	~1.08 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.