Description

1-Benzyl-4-Isocyanopiperidine is a versatile and highly reactive organic building block, specifically an isocyanate derivative of piperidine. Its primary value lies in its role as a key intermediate for synthesizing more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. This compound is essential for medicinal chemists and process development scientists working on new drug candidates, agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system.
• Medicinal Chemistry Research: Used in high-throughput screening and the construction of diverse compound libraries for drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing novel pesticides and herbicides.
• Chemical Biology Probes: Employed in the creation of isocyanate-based probes for studying enzyme activity and protein interactions.
• Polymer Modification: Can be used to introduce reactive isocyanate groups into polymer chains for cross-linking or functionalization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	1-Benzyl-4-Isocyanopiperidine
CAS No.	443890-09-3
Molecular Formula	C13H16N2O
Molecular Weight	216.28 g/mol
Synonyms	4-Isocyanato-1-benzylpiperidine; 1-Benzylpiperidine-4-isocyanate; 1-Benzyl-4-piperidyl isocyanate; Benzyl 4-isocyanatopiperidine-1-carboxylate (related); Piperidine, 4-isocyanato-1-(phenylmethyl)-
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-Isocyanopiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.