Description

Ethanone, 1-(4-Iodo-1H-Pyrrolo[2,3-B]Pyridin-1-Yl)- is a high-value iodinated pyrrolopyridine derivative, a crucial advanced intermediate in modern pharmaceutical research and development. Its core value lies in enabling the synthesis of targeted small molecule therapeutics, particularly kinase inhibitors, due to its versatile functional groups. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on novel oncology and anti-inflammatory treatments.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potent and selective kinase inhibitors targeting various disease pathways.
• Oncology Drug Discovery: Used in the research and development of novel anti-cancer agents, leveraging the pyrrolopyridine scaffold's bioactivity.
• Chemical Biology Probes: Serves as a precursor for labeled compounds used in target identification and validation studies.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Preclinical Candidate Synthesis: Integral to producing compounds for in vitro and in vivo pharmacological evaluation.

Basic Information

Product Name	Ethanone, 1-(4-Iodo-1H-Pyrrolo[2,3-B]Pyridin-1-Yl)-
CAS No.	443729-67-7
Molecular Formula	C9H7IN2O
Molecular Weight	286.07 g/mol
Synonyms	1-(4-Iodo-1H-pyrrolo[2,3-b]pyridin-1-yl)ethanone; 4-Iodo-1-acetyl-1H-pyrrolo[2,3-b]pyridine; 1-Acetyl-4-iodo-1H-pyrrolo[2,3-b]pyridine; 4-Iodo-1H-pyrrolo[2,3-b]pyridin-1-yl methyl ketone; 443729-67-7; 4-Iodo-1-acetyl-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 1-acetyl-4-iodo-
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(4-Iodo-1H-Pyrrolo[2,3-B]Pyridin-1-Yl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.