Description

(8-Phenyl-1,4-dioxaspiro[4.5]dec-8-yl)methanamine is a specialized spirocyclic amine derivative, serving as a crucial advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique fused ring structure with a protected amine functionality makes it invaluable for constructing complex molecular architectures. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its spirocyclic scaffold for bioactive molecule design.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Intermediate in the production of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Academic & Industrial R&D: A valuable tool for synthetic chemists in exploring new chemical spaces and reaction methodologies in medicinal and process chemistry.

Basic Information

Product Name	(8-Phenyl-1,4-dioxaspiro[4.5]dec-8-yl)methanamine
CAS No.	443687-93-2
Molecular Formula	C16H21NO2
Molecular Weight	259.35 g/mol
Synonyms	8-Phenyl-1,4-dioxaspiro[4.5]decan-8-ylmethanamine; 1-(Aminomethyl)-8-phenyl-1,4-dioxaspiro[4.5]decane; (8-Phenyl-1,4-dioxaspiro[4.5]dec-8-yl)methylamine; 8-Phenyl-1,4-dioxaspiro[4.5]decane-8-methanamine; 1,4-Dioxaspiro[4.5]decane-8-methanamine, 8-phenyl-; 8-Phenyl-1,4-dioxaspiro[4.5]decan-8-methanamine
EINECS	Contact for details

Quality Control

Our production of (8-Phenyl-1,4-dioxaspiro[4.5]dec-8-yl)methanamine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.