Description

3-Piperidinemethanol, 5-Amino-4-Hydroxy-, (3R,4R,5S)-Rel- (9Ci) is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block and synthetic intermediate. Its value lies in its unique functional group array—amino, hydroxy, and hydroxymethyl groups on a defined piperidine scaffold—enabling precise molecular construction. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing complex molecules where stereochemical control is paramount for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry influences efficacy and selectivity.
• Catalyst and Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Biochemical Research: Employed as a standard or probe in enzymatic studies and for investigating receptor-ligand interactions due to its structural features.
• Fine Chemical Production: A versatile intermediate for manufacturing other specialty chemicals, dyes, and complex organic compounds.

Basic Information

Product Name	3-Piperidinemethanol, 5-Amino-4-Hydroxy-, (3R,4R,5S)-Rel- (9Ci)
CAS No.	443649-04-5
Molecular Formula	C6H14N2O2
Molecular Weight	146.19 g/mol
Synonyms	(3R,4R,5S)-5-Amino-4-hydroxypiperidine-3-methanol; rel-(3R,4R,5S)-5-Amino-4-hydroxypiperidine-3-methanol; 5-Amino-4-hydroxy-3-piperidinemethanol (rel-(3R,4R,5S)-); 3-Piperidinemethanol, 5-amino-4-hydroxy-, (3R,4R,5S)-rel-; 443649-04-5; (3R,4R,5S)-rel-5-Amino-4-hydroxypiperidine-3-methanol
EINECS	Contact for details

Quality Control

Our 3-Piperidinemethanol, 5-Amino-4-Hydroxy-, (3R,4R,5S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and absorption of moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.