Description

3-(Benzyloxy)-2-Bromo-6-Iodopyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogen substitution pattern, which enables selective cross-coupling reactions and functional group transformations essential for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki-Miyaura, Stille, and Negishi couplings due to the presence of both bromine and iodine leaving groups, offering chemists flexibility in synthetic routes.
• Chemical Biology & Medicinal Chemistry: Employed in fragment-based drug discovery and as a probe molecule for studying protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	3-(Benzyloxy)-2-Bromo-6-Iodopyridine
CAS No.	443307-26-4
Molecular Formula	C12H9BrINO
Molecular Weight	389.02 g/mol
Synonyms	2-Bromo-6-iodo-3-(phenylmethoxy)pyridine; 2-Bromo-3-benzyloxy-6-iodopyridine; 3-Benzyloxy-2-bromo-6-iodopyridine; Pyridine, 3-(benzyloxy)-2-bromo-6-iodo-; 443307-26-4; 3-(Benzyloxy)-2-bromo-6-iodopyridine; 2-Bromo-6-iodo-3-(benzyloxy)pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-(Benzyloxy)-2-Bromo-6-Iodopyridine is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC/GC is provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.