Description

2-Bromomethyl-4-nitropyridine is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive bromomethyl group and an electron-withdrawing nitro substituent, makes it an essential intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Used to prepare functionalized pyridine-based ligands for transition metal catalysis and coordination chemistry.
• Material Science Research: Intermediate in the development of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.
• Cross-Coupling Reactions: Serves as an electrophilic partner in various palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.

Basic Information

Product Name	2-Bromomethyl-4-nitropyridine
CAS No.	442910-43-2
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	4-Nitro-2-(bromomethyl)pyridine; 2-(Bromomethyl)-4-nitropyridine; Pyridine, 2-(bromomethyl)-4-nitro-; 4-Nitro-2-pyridinemethanol, bromide; 2-Bromomethyl-4-nitro-pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromomethyl-4-nitropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with full chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.