Description

3-Pyridinecarboxylic Acid, 2,4-Dichloro-, Methyl Ester is a high-purity, halogenated pyridine derivative that serves as a critical synthetic intermediate. This compound is valued for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the dichloro-substituted pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 2,4-Dichloro-, Methyl Ester
CAS No.	442903-28-8
Molecular Formula	C7H5Cl2NO2
Molecular Weight	206.03 g/mol
Synonyms	Methyl 2,4-dichloronicotinate; 2,4-Dichloronicotinic Acid Methyl Ester; Methyl 2,4-dichloropyridine-3-carboxylate; 2,4-Dichloro-3-pyridinecarboxylic Acid Methyl Ester; 3-Carbomethoxy-2,4-dichloropyridine; 2,4-Dichloro-3-methoxycarbonylpyridine; Nicotinic acid, 2,4-dichloro-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 2,4-Dichloro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.