Description

4-Bromo-2,6-dimethoxypyridine is a versatile brominated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides a reactive halogen site and directing methoxy groups, enabling precise functionalization for complex molecule construction. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules containing functionalized pyridine cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the pyridine scaffold is a key structural component.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as conductive polymers and light-emitting compounds.
• Cross-Coupling Reactions: Acts as a reliable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Item	Detail
Product Name	4-Bromo-2,6-dimethoxypyridine
CAS No.	442686-30-8
Molecular Formula	C7H8BrNO2
Molecular Weight	218.05 g/mol
Synonyms	2,6-Dimethoxy-4-bromopyridine; 4-Bromo-2,6-dimethoxypyridine; 4-Bromo-2,6-bis(methoxy)pyridine; 4-Bromo-2,6-pyridinedimethanol, dimethyl ether; Pyridine, 4-bromo-2,6-dimethoxy-; 442686-30-8 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-dimethoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.