Description

1-(4-((4-Fluorophenyl)Sulfonyl)Piperazin-1-Yl)-3-Methylbenzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a complex heterocyclic scaffold for targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and CNS disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Kinase Inhibitor Development: Serves as a core scaffold for the development of protein kinase inhibitors due to its fused heterocyclic structure.
• Preclinical Drug Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for chemical biology and drug discovery projects.

Basic Information

Product Name	1-(4-((4-Fluorophenyl)Sulfonyl)Piperazin-1-Yl)-3-Methylbenzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile
CAS No.	442572-38-5
Molecular Formula	C25H20FN5O2S
Molecular Weight	473.52 g/mol
Synonyms	1-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile; 3-Methyl-1-[4-[(4-fluorophenyl)sulfonyl]-1-piperazinyl]benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile; 442572-38-5; Benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile, 1-[4-[(4-fluorophenyl)sulfonyl]-1-piperazinyl]-3-methyl-; 1-(4-(4-Fluorophenylsulfonyl)piperazin-1-yl)-3-methylbenzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-(4-((4-Fluorophenyl)Sulfonyl)Piperazin-1-Yl)-3-Methylbenzo[4,5]Imidazo[1,2-A]Pyridine-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.